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Re:Prions, Nearly Indestructible and Universally Lethal, See... by rincebrain on Tuesday December 11, 2018 @09:45AM (#18655564)
A study showed that if they wired two mice's circulatory systems together, one with Alzheimer's and one without, the second one would eventually develop everyone's favorite brain plaques.

https://www.newscientist.com/article/2151909-alzheimers-may-...

So while wiring together two bloodstreams is a bit extreme, and likely to result in most things being transmissible, there's nonzero evidence that you can have a bad day from a blood transfusion.

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