When I tried to use easy_install with the EPD it tried to take me to their repository, for which we don't have appropriate permissions? So I sucked it up and installed some from .dmg's and others from source (matplotlib was difficult). And I found out just because it's Python doesn't mean it's portable - for instance NumPy/SciPy is hardly ever installed on other machines (it's not trivial, as is written here many times), and I find that administrators won't update their Python installation so I've had to re-write bits of my code to accommodate Python 2.3-2.4 at times! But all said, it's a nice tool and hopefully these installation/ version issues will work itself out.

For a basic setup on OS X, I found scipy superpack to be an excellent choice: http://stronginference.com/scipy-superpack/

I've found macports provides a ton of python libraries, like numpy, scipy, and matplotlib, all easily installed from the command line.