Most of the differences I noticed revolved around automatically changing indentation levels(one of the best ways to get uninstalled) and autocompletion which sometimes didn't work(file name completion) and once it refused to autocomplete a certain string without removing the underscores first.

I'm sure a lot of this can be fixed by changing some configuration options, but I don't see a reason to change the editor just for the sake of it. Emacs is awesome in some ways, but it's not my cup of tea.

There is no reasonable way to emulate always on

    :set virtualedit=all

Picture mode is not reasonable. The cursor must go where I put it and stay there, not move in any direction I did not choose.