It feels, to me, like a failure of user interface when someone has to resort to a mouse for input.
Like watching someone trying to play a piano on screen with a mouse. I’m sure it’s possible to compose that way but it looks so clumsy compared to someone fluently playing a keyboard.
EDIT: looks like most of these fonts are just being used for substitutions. I guess I’m neutral on that. Looks nice but I think I still prefer raw text version. Could be convinced either way.
If you copy and paste these examples into a text editor, the font won't have the ligatures and you'll see the characters as you'd expect. They're not inserting weird codepoints to display the symbols; there's a literal < and = next to each other and the font renderer looks them up in a table and renders the mathematical less-than-or-equal symbol.
English script doesn't have many ligatures (ff, and fi are common ones, the bars on the ff are combined, and the dot on the i is subsumed into the bar of the f) but some languages and scripts have lots, I think Arabic does. Cursive English is all ligatures since letters join up differently depending on the letters next to them.