This will inform you, rather than provide a reset or framework: http://webtypography.net/ (and of course, reading The Elements of Typographic Style is worthwhile http://en.wikipedia.org/wiki/The_Elements_of_Typographic_Sty...)

This series of blog posts by Mark Boulton are a good read: http://www.markboulton.co.uk/journal/comments/five-simple-st... If you like that, maybe you should get his book: http://fivesimplesteps.com/books/practical-guide-designing-f...

I haven't used Baseline, but it looks like fairly good framework that has type in mind: http://baselinecss.com/