>2. a lack of face to face contact and the setting of being in my own space keeps me in a semi-permanent doubt/guilt cycle about my work quality and how my effort and reponsiveness is being perceived.

This seems like a personal issue rather than an issue with the concept of working from home. For me, personally, I don't care about when/how people work as long as they're delivering on what I'm asking from them. I may just be extremely fortunate that my team is very responsive but I never have issues with being available for my team or them being available for me and that kind of negates any kind of guilt cycle there could be.