Being sedentary leads to a host of maladies, while constantly doing bootcamps, overtraining, pro sports or cross-continental marathons causes enormous oxidative stress, tissue damage and more risks of premature wear, cancer and aging... so there's a happy medium for a healthy, good quality of and longer life.

Also, between catabolic processes that destroy the body to keep it going and binge eating, there's a happy amount of fasting and cutting calories to a sustainable amount... lipogenesis, ULDLs, and VLDLs generally aren't good.