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Re:Testosterone Treatment and Alleviation of Depressive Symp... by barrow-rider on Wednesday November 14, 2018 @12:21PM (#18451602)
> Findings This systematic review and meta-analysis of 27 randomized placebo-controlled clinical trials involving a total of 1890 men found that testosterone treatment was associated with a significant reduction of depressive symptoms, particularly in participants who received higher-dosage regimens.

Low-T makes you depressed, or correlates with depression. Cue the inevitable "soyboy" epithets and related wankery.

Re:Testosterone Treatment and Alleviation of Depressive Symp... by copperx on Wednesday November 14, 2018 @12:42PM (#18451827)
Is soy associated with lower levels of testosterone?
Re:Testosterone Treatment and Alleviation of Depressive Symp... by jrapdx3 on Wednesday November 14, 2018 @01:11PM (#18452153)
IIRC soybean products (like tofu) are said to contain small amounts compounds with estrogen-like properties. Hence males consuming significant quantities of these products may be affected by higher than normal level of circulating estrogens.

I don't know how much tofu ingestion is required to produce a noticeable effect (such as gynecomastia), but I assume it would have to be a major dietary component. In Asian countries, soybean consumption is much higher than typical in the US, so perhaps more likely to be an issue there. Might be worth a literature search on the subject, but I haven't done that, so I don't know if it's been verified.

Re:Testosterone Treatment and Alleviation of Depressive Symp... by mkbgw on Wednesday November 14, 2018 @01:30PM (#18452368)
This is quackery, as shown by this meta-study: "Soybean isoflavone exposure does not have feminizing effects on men" https://www.ncbi.nlm.nih.gov/pubmed/20378106.
Re:Testosterone Treatment and Alleviation of Depressive Symp... by jstewartmobile on Wednesday November 14, 2018 @02:17PM (#18452917)
Mark Messina (the study's author) is a shill for the soy industry.

"M.M. regularly consults for companies that manufacture and/or sell soyfoods and/or isoflavone supplements, and he is the executive director of the Soy Nutrition Institute[0], a science-based organization that is funded in part by the soy industry and the United Soybean Board."[1]

More people would trust science if more scientists were not whores.

[0] https://thesoynutritioninstitute.com/author/dr-mark-messina/ [1] https://www.fertstert.org/article/S0015-0282(10)00368-7/full...

Re:Testosterone Treatment and Alleviation of Depressive Symp... by wowzap on Wednesday November 14, 2018 @01:06PM (#18452100)
Yes, soy destroys almost all sexual organ/sexual development facets of the human experience. Just last week they found that women who were fed soy formula when they were babies have a higher risk of experiencing bad cramps during their period.
Re:Testosterone Treatment and Alleviation of Depressive Symp... by GordonS on Wednesday November 14, 2018 @01:10PM (#18452150)
How do you explain China's population of 1.3 billion?
Re:Testosterone Treatment and Alleviation of Depressive Symp... by jstewartmobile on Wednesday November 14, 2018 @02:26PM (#18453016)
Could be that different people with different genetics have different reactions to different foods throughout their lifetimes.

Most asians become lactose intolerant after infancy. Many western europeans don't. Just because the Chinese can handle soy like champs doesn't mean everyone else can.

Re:Testosterone Treatment and Alleviation of Depressive Symp... by greenshackle2 on Wednesday November 14, 2018 @01:41PM (#18452508)
Soy is probably the most researched food in history, you can reach pretty much any conclusion you want if you cherry-pick your studies.

Analyses that don't cherry pick tend to conclude it's pretty safe.

Re:Testosterone Treatment and Alleviation of Depressive Symp... by mkbgw on Wednesday November 14, 2018 @01:30PM (#18452377)
This is quackery, as shown by this meta-study: "Soybean isoflavone exposure does not have feminizing effects on men" https://www.ncbi.nlm.nih.gov/pubmed/20378106.
Re:Testosterone Treatment and Alleviation of Depressive Symp... by virmundi on Wednesday November 14, 2018 @02:02PM (#18452762)
I’m curious about who they measured. We already know that the US population of 30 year olds has roughly half the testosterone of their grandpas at the same age. If you’re only measuring the sick, so to speak, you might not find anything.

For anyone down voting, an open question in the paper is “do Asians have factors that might mitigate the phytoestrogens?” They don’t know.

As to evidence that levels are dropping, https://www.healio.com/endocrinology/hormone-therapy/news/pr...