Know your pay-offs. Gambling your health to enrich someone else, while you scrape by with pennies, is a last resort. Gambling your health for tremendous gains is a fair choice.

These are gambles humans leaving Africa and navigating the oceans made. (The cost of loss was death.) It’s a risk we’ll face expanding to the Moon and Mars and Alpha Centauri. Be thoughtful about the risks you take—not all are offered equally—but don’t discard them outright for being risky.