Regarding point #3 -- In the 80's, clinicians at Kaiser Permanente recognized that success in a weight-loss program was correlated to stresses experienced during childhood. This lead to the Adverse Childhood Experiences study, using a measure which scores people on a scale of 0-10. Those with scores of >3 (factors such as separated parents, child abuse, sexual abuse, food insecurity) have significantly worse outcomes in later life. https://en.wikipedia.org/wiki/Adverse_Childhood_Experiences_...