Sure, if you want to keep the 'influence' between the two systems to a minimum.

If you allow the mutation of the subset reality by a soul in the meta-heaven, then you can have it all operate in a single universe; the soul is capable of adjusting the nondeterminism of particles in the brain, thereby making decisions happen that appear random to us, but are informed by a higher system of reasoning. In the way that a programmer might adjust constants, or a video game player might choose stats.

And just want to reiterate: I'm not trying to advance this explanation! Just fun to think about.