I think it depends less on the app and more on the negotiating power/experience of each party.

Not only that, but the market it's based in - our poster's app happens to be in healthcare, which has its own 800-lb gorillas (large hospitals and pharmas) and its own smaller players too.

Obviously the poster thought that the app would become lucrative enough to justify a $160k investment. If the payoff looked really huge, you could justify being a little more stingy with the options. Just sayin'. (From the guy who doesn't have a lot of options because his app is in healthcare too)