I like the idea behind Macchiato but unlike it's Clojure cousin, Luminus, there doesn't seem to be any documentation on database access. I especially like HugSQL in Luminus. Is it possible to use it with Macchiato?

There is macchiato-sql [1] which is modeled on HugSQL. I've used it for a couple of projects, but YMMV. I tend to use sequelizejs since it works with most databases and it's well documented.

[1] https://github.com/macchiato-framework/macchiato-sql

Bejesus, Sequelize.js is a LOT more work than HugSQL. I keep looking at Macchiato but without a Clojurescript database layer I can't see it being useful.

I mean if you're on Node, it's not going to be any better with plain Js either. Stuff like this is precisely why I prefer the JVM ecosystem myself.