And it costs more than a desktop + netbook combo.
So I'm not concerned if I can't upgrade my hardware down the road. Having everything soldered in place means I get a lighter product with fewer points of failure.
Do hardware parts really fail enough to make it worth eliminating cpu sockets, memory slots, sata, pci express, etc?
Creepage among memory chips is also possible. RAM doesn't sit as snug for the entire life of your computer. It creeps out a little bit over time and allows for dust to prevent conductivity between the chip and the slot. Having everything soldered in place is much better.
The biggest issue, though, is all the added space required for the housing. The slots, connectors, clips, etc make the product bulkier. While that's fine for a desktop it's not ideal for a mobile device.
Not sure that CPU replacement is -that- common an upgrade, even for desktops. Every few years, the latest and greatest CPUs seem to use a new socket anyways.
Only problem is that the 6-core CPUs are $1000 :)
In my home office I have a MBP w/ a Microsoft Ergonomic Elite Keyboard w/ one 24 inch Cinema display (Apple) and one 19 inch flatscreen. I also use an Intellimouse.
As far as I can tell, that's the best of both worlds. Take the MBP on the road when you need to; stay cozy at home all the rest of the time.