I think an argument could be made that we're not really doing a great job of dealing with alcohol as a destructive and dangerous drug.
https://www.google.com/amp/s/amp.theguardian.com/society/201...
This isn't an argument against legalization, it's an argument against normalizing drug use via social and cultural acceptance and promotion.
The counter argument is that while it is still causing many ills, it did not "destroy the fabric of society" or something like that. The thing is that many people enjoy drinking alcohol, so finding a good balance is difficult.
Very similar things can be said about alcohol (just look at how many people are addicted to it), yet we have learnt how to live with that drug. The same arguments against alcohol were used in the prohibition era.