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Re:Effects of High Fat Diet may Last for Generations by vibrato on Saturday October 13, 2018 @12:11PM (#18208641)
Exactly, it’s hard to generalize mouse dietary studies to humans because they’re not anything close to an apex predator, humans are. Our biology is evolved to preferentially run on fatty meat from large game animals (that are now mostly extinct thanks to our prowess).
Re:Effects of High Fat Diet may Last for Generations by mycorrhizal on Saturday October 13, 2018 @12:33PM (#18208755)
I'm sorry, but this is just so wrong. I'm not saying humans can't eat meat, but if you compare the digestive track and other physiological factors of humans to animals that actually evolved to eat meat like lions the difference is startling. On the spectrum of cow to lion we are very far from the lion end so to say humans "evolved to preferentially run on fatty meat from large game animals" is just plain wrong.

Here is a somewhat entertaining video with some specifics and sources. https://www.youtube.com/watch?v=XmXynDLkbXY

There is also a ton of anthropological data on how our diets actually did evolve and although there are exceptions the gist is that we mainly relied on gathered plants with occasional meat.

Re:Effects of High Fat Diet may Last for Generations by masonic on Saturday October 13, 2018 @04:11PM (#18209771)

  On the spectrum of cow to lion we are very far from the lion
Do you seriously not understand that cows are ruminants?
Re:Effects of High Fat Diet may Last for Generations by mycorrhizal on Saturday October 13, 2018 @07:37PM (#18210584)
I actually do. My point was that on a spectrum of "apex predator totally tailored for eating meat" and total herbivore able to digest cellulose we are far from both ends.

The gp specifically stated we have "evolved to preferentially run on fatty meat from large game animals" and that is just plain wrong.

Re:Effects of High Fat Diet may Last for Generations by vibrato on Tuesday October 16, 2018 @09:27PM (#18234863)
How many stomachs do humans have? How much energy do we obtain from fiber?