What was being described is going to programming from a RISC-like design processor to a CISC-like design processor, and how they felt constrained after doing so. It likely does feel more constraining (I don't really remember how I felt about it back when I did it, but I also went the other direction, and only in the context of classwork), but in the end, most people are programming a level removed from that anyways.
There used to be quite a lot of arguments about what design was better (IMO mostly fueled by Macs running a RISC processor and Windows running a CISC processor, at least until Apple switched to x86). I find it slightly comical that both designs ended up in a fairly similar place though (with RISC processors adding extra instructions, and CISC processors adding more registers, even if mostly just logical registers).