Re:Transmission of cancer by a single multiorgan donor to 4 ...
by mataug on Monday September 17, 2018 @08:37PM
(#18011407)
So would it be valid to say that all transplant recipients have a significantly higher risk of developing cancer ?
Re:Transmission of cancer by a single multiorgan donor to 4 ...
by Scaevolus on Monday September 17, 2018 @08:56PM
(#18011500)
Yes, but it's largely because of the lifelong immunosuppression to not reject the transplant reducing the body's ability to combat cancer. Of course, it's still better than not having that organ!
https://www.cancer.gov/about-cancer/causes-prevention/risk/i...
Re:Transmission of cancer by a single multiorgan donor to 4 ...
by mhalle on Monday September 17, 2018 @11:45PM
(#18012302)
In addition, different organs need different amounts of immunosuppression. Livers are used to filtering random things and thus the body is more tolerant of livers (needs less immunosuppression). Some older liver transplant recipients can actually drop their immunosuppression drugs completely.
The exact transplant protocol also influences long-term levels of immunosuppression and thus cancer risk.
Re:Transmission of cancer by a single multiorgan donor to 4 ...
by throwaway76543 on Monday September 17, 2018 @08:58PM
(#18011514)
Yes, but not just from the transplant. The immunosuppressant drugs following a transplant also increase your risk of cancer. Dramatically for certain types of cancers.
I.e. they didn't find evidence of it at the time of donation.