No. ClojureScript works with React Native, and in that case you can use the Figwheel REPL. See http://cljsrn.org

Ambly can be useful in other situations where you are not building a React Native app, but still want ClojureScript driving things. For an example with Ejecta, see http://blog.fikesfarm.com/posts/2017-04-29-clojurescript-eje...