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Re:Infectious Theory of Alzheimer's Disease Draws Fresh Inte... by narrator on Sunday September 09, 2018 @01:31PM (#17946878)
If anyone has been looking at TauRX's phase 3 trials[1], methylene blue is ridiculously cheap, has been around for 100 years and stops Alzheimers progression better than any other drug. Tau is working on a slightly modified form that is basically putting it in a capsule and they'll sell it for $50 a pill probably, but that's the only way that anyone will believe it actually works.

Methylene blue is a potent antimicrobial that easily penetrates the blood brain barrier, so it working so well would be consistent with Alzheimers being an infectious disease.

[1]https://content.iospress.com/download/journal-of-alzheimers-...

Re:Infectious Theory of Alzheimer's Disease Draws Fresh Inte... by mrtnmcc on Sunday September 09, 2018 @05:01PM (#17947768)
Other studies of mild to moderate Alzheimer's patients showed no improvement with Methylene blue,

https://www.alzforum.org/news/conference-coverage/first-phas...

Also I'd generally be more skeptical as the green urine it produces could be a strong placebo enhancer that is hard to control against.

Re:Infectious Theory of Alzheimer's Disease Draws Fresh Inte... by DenisM on Sunday September 09, 2018 @08:00PM (#17948466)
Monochromatic red light in the bathroom should take care of placebo problem? Or red glasses, something like that. Maybe artificial piss color.
Re:Infectious Theory of Alzheimer's Disease Draws Fresh Inte... by tcj_phx on Sunday September 09, 2018 @03:04PM (#17947244)
Methylene blue is also an monoamine oxidase inhibitor. I add it to my dog’s food to boost her metabolism. She blew her knee out a year ago (common injury for large 10yo dogs) but has mostly recovered without the surgery the vet said she’d probably need. (I use a variety of interventions with her.)

Methylene blue should not be combined with the later anti-depressants that focus more on serotonin (SSRIs, etc.), as this can cause serotonin toxicity: https://www.apsf.org/article/methylene-blue-and-the-risk-of-...

> Tau is working on a slightly modified form that is basically putting it in a capsule and they'll sell it for $50 a pill probably, but that's the only way that anyone will believe it actually works.

Patent medicines [1] are still as popular as they ever were. Science made some inroads in the early 20th century, before the hucksters regrouped, with new prescription-only FDA approved nostrums.

[1] https://en.m.wikipedia.org/wiki/Patent_medicine

Re:Infectious Theory of Alzheimer's Disease Draws Fresh Inte... by delbel on Sunday September 09, 2018 @02:40PM (#17947158)
thanks for your post. That would be funny if the cure is to drink the "Methylene Blue Kool Aid"