* Stateful server. When you enter a room, you immediately see the conversation that has been going on there. That means it's possible to have conversations that are long-spanning (more like email) because you don't necessarily have to see replies scrolling by
* Integration with Stack Overflow accounts and reputation. Bad behavior is almost completely eliminated thanks to the tie in to the reputation system (you need some rep on Stack Overflow to chat, for example)
* Super slick user interface. You have to see it to believe it. Try it for a while and see.
The reputation thing is both a positive and a negative. It's going to be a barrier to entry for some people - both good apples and bad. Hard to know the ratio...
The interface is nice, but I like my IRC client too.
No more pasting @ nomorepasting.com
EDIT: Well you do have to go to gist to post code but it does INLINE it into the chat!!!