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Re:OxyContin billionaire has patented a drug to wean addicts... by mveety on Saturday September 08, 2018 @04:56PM (#17942743)
Buprenorphine also increases cardiac mortality by increasing the QT interval. Buprenorphine is used over methadone mostly because its a partial agonist of the mu-opioid receptor which basically limits how high you can get.
Re:OxyContin billionaire has patented a drug to wean addicts... by stochastic_monk on Saturday September 08, 2018 @06:21PM (#17943110)
You’re right! I hadn’t known that buprenorphine also caused it, but it seems all of the drugs used for that purpose. I did find a 2013 study stating that the effect was significantly less than that from methadone, but it’s good to know that both come with cardiac risks.