Wow thanks for your post. I had to look up and I was surprised that antibiotics can damage your mitochondria. But it makes sense because I was told, back in biology, the mitochondria were actually a bacteria and "swallowed up" by mammal cells. (forgive me, that's a extremely trivial recall of my memories and I am not an expert in this field)

If you are interested (and very brave, there are risks here), apparently there is a SARM that can help your mitochondria grow back. It's called Stenabolic SR9009. I have never tried it (because I have no need), but I'd be interested in what you think about it. You can find information on it online, I don't want to post anything because I am not qualified to vet the information -- information is all over the web however.

For me the experience has made me less risky in general (this was a standard 10 day treatment for sinus infection). Fasting / exercise for now. My biggest issue is the gut and repopulating bacteria. Once that's in order I may try something like the Stenabolic.

The negative effects of Ciprofloxacin and other fluoroquinolone antibiotics was touched on in this post:

https://news.ycombinator.com/item?id=13273770

If it affected your tendons Magnesium is recommended. I'd also speculatively suggest iodine (a few mg per day) and glycine (1-20 grams per day). I am not a doctor, but then that's who prescribed you that crap ;-)

I have chronic fatigue likely brought on by mitochondrial dysfunction. Iodine ended a 12 month long mono infection and is the difference between having enough energy to spend the day reading.

I'm curious what you mean by that. It sounds like an odd way to frame it.

I've personally never struggled so hard to recover from anything. I couldn't do it justice in a short post. Lost 75 pounds in a 45 days. Heartrate over a 100 for a month.

Here is a link to another nature article on it: https://www.nature.com/articles/d41586-018-03267-5

Yes, I've recovered from long term prescription drug use. It was awful.

I just thought mitochondrial damage was a strange framing.

Thanks.

Edit: The article does talk about mitochondrial damage, though it didn't appear at first glance to address this. It's towards the end of the article.