It is difficult but not impossible to overdose on caffeine and die. I'm not sure if this is the toxicity that the previous poster meant, but it could be. It appears that 30 cups of coffee is about the threshold where you get to serious danger, but that sounds insane... I've got terrible nausea after four or five cups of light roast (which has more caffeine).

Caffeine pills & powder are far more dangerous. It is very easy to overdose on them, and death is not out of the question. It still isn't common.

With marijuana, it is virtually impossible to have an overdose that kills you (It's very difficult to find sources on CBD/THC overdose):

> An overdose on marijuana is dissimilar to overdoses on other drugs because marijuana consumption, in and of itself, is not life-threatening. But using too much of the drug can have hazardous results, which may increase the risk of death.

> For instance, someone who consumed a lot of marijuana may be unaware of their environment, which can lead to accidents or falls. Furthermore, marijuana intoxication has been linked, in some studies, with psychosis,3 a condition in which the individual is disconnected with reality, typically resulting in hallucinations, delusions, or extreme paranoia. A person who is having a psychotic episode may put him or herself in dangerous situations due to confusion or detachment. [0]

Synthetic MJ (K2) is far more dangerous, though.

[0]: https://www.projectknow.com/research/marijuana-overdose/