The nightmarishly complex wheat genome finally yields to scientists

Re:The nightmarishly complex wheat genome finally yields to ... by Steel_Phoenix on Saturday August 18, 2018 @12:54AM (#17786938)

The challenge would be making sure that only that modified wheat was harvested. I'm sure it could be done, but a needle in a haystack seems much easier to find than a conventional wheat in a celiac friendly wheat stack.

I'm not sure genetic mapping is really the core of the issue anyway. What we need is the equivalent of a reverse vaccination, since celiac is essentially an immunity to wheat. Such a concept might do for chronic disease what vaccination did for acute.

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Re:The nightmarishly complex wheat genome finally yields to ... by code_duck on Saturday August 18, 2018 @01:50AM (#17787083)

Sure, that would be difficult. Keeping wheat out of even dissimilar grains is currently a challenge for food producers and processors. The test would be the same, though, as testing any other grain for contamination, which is routine - test for gluten.

As far as future treatments, this clinical review https://www.gponline.com/coeliac-disease-clinical-review/gi-... concludes that

“Future potential treatments for patients with RCD include the development of genetically detoxified grains, oral and intranasal 'coeliac vaccines' to induce tolerance, inhibitors of TTG, and detoxification of immunogenic gliadin peptides via oral peptidase supplement therapy.”

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