What would be the benefits of the 3D VR? There will always be a 2D bottleneck on your eyes' retina. The most important perspective clue I would say is temporal sampling. For dynamical systems, Takens theorem says that a high dimensional topology can be restituted by the sequential sampling of a single variable alone. It seems likely to me that our perception generally works by this principle. That being said, I think we are quite heavily hardwired to 3D perception. I suspect these circuits cannot be wholly overridden.