Michael Crichton/Outbreak type stuff isn't what scares me. It is going into a hospital for a routine hernia surgery or dental surgery and getting an infection that responds to nothing. It could happen right now, but is unlikely. The chances will increase as antibiotic resistance spreads. It's not people screaming in the streets, it a more gradual change to a new normal where routine care may no longer be routine, with maybe occasional bursts of incidence at some hospital or other. There will be a lag-time to making new antibiotics, and honestly it's not now an area of focus for Pharma for economic reasons.