There's also a significant body of literature that does not fail to find such associations.

Feel free to add citations, but the most recent findings seem to suggest no negative impacts.

Psychedelics bring forth what needs to be looked at; if one doesn’t have an intention or support to do that, they may want to want until they do.

The same could probably be said for falling in love or starting a company as well.

In fact, my guess is that romantic relationships and entrepreneurship probably trigger “underlying mental issues” with at least as much frequency as psychedelics.

If there is, then a good meta analysis should be possible or already done.