I mean, all you’re saying here is that there are disadvantages to being male / masculinized. All you’re doing by signing up for TRT is signing up for the longevity of the average man vs. the longevity of the average woman or eunuch.

Are you suggesting that everyone who naturally produces testosterone (i.e. is on a constant dose of “endogenous anabolic androgenic steroids”) would be better off if they stopped doing so? If not, then there’s got to be a genetic profile + dose level at which the advantages of TRT outweigh the costs.