I did it. My ecommerce company is doing well enough to comfortably support two people (ramen profitable --> pizza profitable --> casual dining profitable... we're just short of casual fine dining profitable, but if linear growth continues we'll be there in 6 months).

I'm not sure that I have very many useful lessons for other people, other than that it is possible to make money by selling stuff online while doing your own supply chain/order fulfillment. It took more than three years of SEO growth for us to hit critical mass.