I find it hard to imagine most social norms, and much of what we consider to be good/bad behavior, is reliant on what we're "wired" towards; influenced by, sure, but I would imagine most of it is along the lines of "regardless of human nature, this is the way we should operate". Respecting monogamy, at least in America, is one of those things: regardless of how we naturally would like to behave, we are expected to (and promise to) respect the sanctity of marriage. That one fails to is not excused by our wiring; we obviously should be capable of exceeding that. It is, supposedly, one of those abilities that make humans as a species notable.

And if we go to an extreme, that you operate solely on your wiring and nothing else... well, you're hardly a modern human at that point.