I used the Microsoft IntelliMouse Optical for years until I discovered the SteelSeries Sensei. It is a gaming brand, which means you will have useless lights on it but it still has the symmetric design like the IntelliMouse and has additional buttons on each side that can be remapped with the (not soooo bad) driver software. Tangential, but I can't understand how left handers can be neglected by peripheral hardware makers this much. Do they assume that just EVERYONE uses the mouse with their right hand?

I got bit by SteelSeries Sai when right button switch wore out (classic double click disease) and I was unable to source a replacement switch.

Plus the thing failed to initialize in a few EFI because it takes way too many seconds to start and show up on USB bus.

The replacement Logitech G905 works much better, though it has one fewer usable button.

I'm not lefthanded but I also owned a steelseries sensei, its a very nice ambidexterous symmetric designed mouse. I used it mostly as a push-to-talk button but now I just stick with a g502 logitech prometheus since I tend to favor heavier mouse.

Its a shame there aren't more left-handed mouses developed, but the market isn't nearly as big as right handed mouses.

I wish left handers got some taste of the multi-button mice.