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Re:Ask HN: WebMail packages for personal use by mike-cardwell on Monday September 27, 2010 @01:28PM (#1732434)
DBMail is the only mail server I know that uses a MySQL backend to store messages:

http://www.dbmail.org/

It does run on OSX. You'd then need to install a webmail client which can talk to DBMail via IMAP. Most of them work this way. My personal favourite is called Roundcube:

http://roundcube.net/

It's written in PHP. Of course, you'd need to install a web server too.

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