I used to think the same thing back when I used Clojure + ClojureScript. Hah, what idiot would choose Javascript over my god tier Clojure/Script setup?

Well, one day I actually tried to build a company and my cofounder just couldn't be fucked to learn Clojure. We decided on Node. I was forced to learn how to play nice with Javascript where I learned how to appreciate it.

Nowadays, I have a hard time justifying something like Clojure/Script over Javascript. Same with Elixir. And I am very wary of people who can't spot trade-offs since that was how I used to be, and I was wrong. I just didn't have enough experience.

There is no best. There are only trade-offs. Elixir/Clojure might be a good business decision for your project, but if you can't concede any positives to Javascript, I don't think you have a firm grip. And in the end it's always a business decision, not a technical one.