I'm not sure it helps to describe depression as a chemical state. Happiness and sadness are also "chemical" states.
Re:Anthony Bourdain has died
by nucleardog on Friday June 08, 2018 @03:23PM
(#17268849)
It's helpful in that it's telling what it isn't.
Depression isn't just an error of thought. It's not a lack of understanding about how great your life really is. It's a hardware error causing the software to malfunction.
Depression is not hopelessness. It is not sadness. It is not unhappiness.
Depression is a chemical state in the brain which leads to lower general emotion levels. Depression is when you feel nothing. Depressed people may self-harm to "feel something".