> You're effectively required to grok all of JS, Reason, Bucklescript, and OCaml at once, and draw from all of them to piece together your code.

This was my experience as well. Also, while it may theoretically be possible to compile native code with reason, the core focus of reasonml is javascript frontend development at the moment.

> On the native side, since Reason's just a syntax transform: yes, they work with Reason too. But the native workflow is currently work-in-progress and needs polish.

https://reasonml.github.io/docs/en/faq.html