In high school I learned 6502 (Apple II) which prepared me for the college course that was in 6809. I enjoyed the 6809 more, but I still have a soft spot in my heart for 6502. I also had a course on 8088 in college and really didn't like it at all.

Looking back, I had college courses on assemblers for 6809 (EE dept), 8088 (CSci), and IBM 370 (CSci - the banana book rocked). I wonder if that goes on anymore today.