You can, but it's not a lot of fun. I did it for years as a modified BBB element in 5/3/1. I have, at various times done 5x5 squat past 4 plates as well. Didn't last more then 3 weeks before I had to back off, I'm too old to recover from that, but I was working Texas Method at 415 lbs, which was just as hard as it sounds.