I've run CopperheadOS a while ago (https://copperhead.co/android/) and in my opinion it's only gotten worse. As someone else mentioned; the "Google Play Services" are an essential part of apps these days. So expect any "mainstream" app not to work. You're forced to use open source alternatives from F-Droid (https://f-droid.org/en/)

Yes it's possible, but i wouldn't call it a "high quality android experience"