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Re:The aging mind: neuroplasticity in response to cognitive ... by killjoywashere on Sunday April 29, 2018 @12:55PM (#16952786)
The evidence on statins is so strong that DeBakey put himself on one when they first came out. He lived to 99 and was sharp to the end. More than a few have opined we should add one to water supply.
Re:The aging mind: neuroplasticity in response to cognitive ... by vertexFarm on Sunday April 29, 2018 @01:30PM (#16952953)
This isn't evidence, this is marketing and anecdotes.
Re:The aging mind: neuroplasticity in response to cognitive ... by eyeball on Sunday April 29, 2018 @02:13PM (#16953159)
Things like this make me ask ... would he have been sharper without them?

That’s what I run into with my doc. “You seem sharp to me”. Yeah, I’m a resonably smart guy, but could I be better if I skip these? Slowdown may not be apparent to others, but it is to me.

Re:The aging mind: neuroplasticity in response to cognitive ... by neffy on Sunday April 29, 2018 @02:34PM (#16953241)
Not a doctor... observed some interesting side effects with my parents on these, and would personally err on the side of caution with them. If you do come off though, do it gradually - also there are different types, so it may be worth looking into that.
Re:The aging mind: neuroplasticity in response to cognitive ... by jonhendry18 on Monday April 30, 2018 @06:17PM (#16962933)
"would he have been sharper without them"

Probably not? It'd be pretty unusual for an already sharp person to become sharper at age 80.

Re:The aging mind: neuroplasticity in response to cognitive ... by eyeball on Tuesday May 01, 2018 @11:08AM (#16967618)
Sharper at 80 with statins or without statins was the question, not sharper at 80 than at 70.
Re:The aging mind: neuroplasticity in response to cognitive ... by jonhendry18 on Tuesday May 01, 2018 @01:21PM (#16969103)
Since he kept working for another 19 years, including supervising heart surgery on Boris Yeltsin, he probably didn't suffer much of a decrease in sharpness on statins, if any.
Re:The aging mind: neuroplasticity in response to cognitive ... by fthssht on Sunday April 29, 2018 @07:32PM (#16954533)
True, evidence looks more like this:

Two well-done meta-analyses of statins for primary prevention showed no mortality benefit. After the exclusion of four trials with serious risks of bias, the relative risk of cardiovascular events associated with statins was 0.99 (95% confidence interval, 0.90 to 1.08).2,3

http://www.nejm.org/doi/full/10.1056/NEJMc1207079

Re:The aging mind: neuroplasticity in response to cognitive ... by killjoywashere on Sunday April 29, 2018 @04:35PM (#16953798)
oh for pete's sake, let me google it for you: https://www.uspreventiveservicestaskforce.org/Page/Document/...

Now, as for mental health, the FDA has added no warnings despite decades of use, and the mechanism of action strongly suggests statins would be protective if anything (by directly and significantly reducing vascular dementia). Here's a package insert from the FDA's website: https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/02...

Also, I'm not raging statin advocate, the real answer is diet and exercise. The American lifestyle is a catastrophe.

Re:The aging mind: neuroplasticity in response to cognitive ... by vertexFarm on Sunday April 29, 2018 @07:55PM (#16954645)
Believe it or not, relying on other people to google your claims is not a good way to present evidence.

I can find confirmations and denials of literally any concept in the universe on google.

This is more a general rule when discussing medicine, not so much a denial of this specific drug.