In my practical experience at the grocery store, avoiding HFCS will at least accidentally lead you to a lower sugar diet. This is mostly due to the fact that at a typical grocery store you won't be able to find many of the more processed goods that don't have HFCS in it (there is literally 1 brand of bread out of 10-15 at the local Publix without HFCS), so you'll basically be forced to buy more raw vegetables, fruits, meats, etc.