Yes. It broke many add-ons that were important to me. I'm hanging in there doing my usuals with the 52 ESR version, although it has broken a half-dozen of them. Many of the Quantum 'replacements' have been severely restricted in functionality.

Unless the situation improves, when the ESR expires, I'll be switching to FF forks permanently. E.g. Pale Moon. And there are others in the works, like Waterfox.