I don't have personal experience, but my understanding is that GTK is much easier since it's in C; QT makes use of some C++ features like inheritance that don't have a direct analogue in Rust that makes it hard. I've heard of several people doing things, but am not sure there's a particular go-to amazing solution at the moment.

The last time I looked into it, there was this project: https://phabricator.kde.org/source/rust-qt-binding-generator...

But it was in the prototype stage then.