The enemy within: Gut bacteria drive autoimmune disease

Re:The enemy within: Gut bacteria drive autoimmune disease by code_duck on Sunday April 08, 2018 @12:40PM (#16786909)

Having one autoimmune disease increases the likelihood that you have or will develop another one. They also have cross-reactivity on tests.

For instance, false positives on the TTG/IGA for celiac are 2% for healthy patients, but rise to 20% for subjects with type 1 diabetes.

Celiac patients have a drastically higher rate of Hashimoto’s, autoimmune thyroid disease: https://www.newsmax.com/t/newsmax/article/718160?keywords=ce... and also the liver disease cited in the article: https://www.verywell.com/celiac-disease-and-liver-diseases-5...

Celiac patients also suffer higher rates of MS: https://multiplesclerosisnewstoday.com/2015/05/14/celiac-dis... MS doesn’t seem gut related on the surface, but you can get almost identical neurological symptoms from celiac. I know because this is what drinking beer does to me.

So, the roots of all of these diseases could definitely be related.

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Re:The enemy within: Gut bacteria drive autoimmune disease by vanderZwan on Wednesday April 11, 2018 @07:10PM (#16816623)

> So, the roots of all of these diseases could definitely be related.

Well, yes, but by definition they already have one connection at the root: the immune system. So increased comorbidity could also be explained by having a kind of immune system that fundamentally is more likely to develop auto-immune diseases.

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