I often see antidepressants held to more stringent standards of evidence, theoretical backing, and safety than other treatments. It's pretty common to see someone claim that the chemical imbalance theory is bunk and that antidepressants don't outperform placebo, then glowingly endorse something else with markedly less scientific support as a treatment for depressive disorders (e.g. exercise, supplements, insight-oriented psychotherapies, mindfulness meditation).