I too took the first iteration, and it was... quite terrible.

The lectures were OK, but the homework was more than challenging. Not only had you to battle with the topic itself, but then you need to magically acquire knowledge in some totally unknown topic (I think it was genetics) and wrangle the quite baroque representation of that topic shoehorned in a programming language that is totally not made for it.

I was on the verge of despair because of those secondary problems. Really.