I voted it down because I didn't think the tone was constructive. It seemed to be accusing Thiel of not considering the big picture, when in fact Thiel is considering something much, much larger. You're asking about differential pricing of prescription drugs, while he's wondering about the impact of a spot market on human organs. What did you think of that part?

Thiel isn't arguing that globalization is a done deal. If anything, he agrees that what we have is astonishingly incomplete: "we stand at a level of globalization that compares with the previous peak year of 1913". Rather, he's asking whether the economic world as we know it could withstand true globalization.

But to answer your question: yes, I think it's only to be expected that corporations will seek to maximize their profits through price discrimination. And also to be expected that true globalization will make this more difficult to do. But while it's clear that those paying the higher price would benefit in the short-term from paying a lower price, it's not clear to me who would benefit in the long-term from forcing companies to choose a single set price somewhere in the middle. It probably depends on how this would be enforced.