I've experienced lonliness on the job but I've come to realize it has more to do with having meaningful work than meaningful relationships. If I'm doing work that is contributing and adding value I will not care at all about the people I'm surrounded by or if they even know I exist. When I'm underworked I start to feel excluded and isolated.

Currently I'm bordering on overwork and I find socializing taxing. When I work from home I do twice as much work but I don't need to sleep on the couch after work.