The screen from the Lenovo Twist is a drop-in IPS upgrade and entirely shielded by a protective touchscreen that's removable. I have a slide deck that explains the procedure in detail: https://anddevw.com/gdgsf-chromepad-chromium-for-thinkpad/

From what I heard, it's vulnerable to pressure from the rear, like if you jam it in an overpacked bag. But that's the original panel, I don't know about the Twist panel, thanks for the link.

Still, from what I gather the IPS panels suck a bit more power than the TN panels (not a huge difference, though), and for my use (travel PC getting lugged all over the world in hand luggage) I'm primarily interested in ruggedness and battery life. I use it to browse and read email, with the occasional Youtube video, not for anything color critical. I would be much more interested in upgrading the mediocre built-in speakers, apparently you can use the speaker from a Nexus 6P for a nice boost in volume and quality.

The speakers really are exceptionally terrible, but upgrading them seems like a lot of work for not a lot of improvement. There's a detailed guide to the speaker upgrade over here: https://petrosprojects.blogspot.com/2017/12/thinkpad-x220-sp...