For what it's worth, Windows NT 4.0 ("full windows") ran on DEC Alpha, and using FX!32 emulation, executed x86 Win32 apps. There was even a 64-bit build of NT running internally at Microsoft as a proof-of-concept, but wasn't publicly released.

https://en.wikipedia.org/wiki/DEC_Alpha

https://en.wikipedia.org/wiki/FX!32

https://technet.microsoft.com/en-us/library/2008.08.windowsc...